Insomnia Disease

BASICS

DESCRIPTION
Difficulty in falling asleep or maintaining sleep, intermittent wakefulness, early morning awakening or a combination of these. Can be:
  • Transient - due to a life crisis, bereavement, change in environment or concomitant illness
  • Chronic - associated with medical and psychiatric conditions or drug intake
  • System(s) affected: Nervous
  • Genetics: N/A
  • Incidence/Prevalence in USA: Affects an estimated 35% of the adult population. One of the most frequent complaints in primary care practice.
  • Predominant age: Elderly
  • Predominant sex: Male = Female
SIGNS AND SYMPTOMS
  • Perceived reduction in sleeping time
  • Initial insomnia - difficulty initiating sleep at usual time
  • Middle insomnia - wakefulness during the usual sleep cycle, "tossing and turning"
  • Terminal insomnia - early awakening
  • Daytime sleepiness and napping
  • Tiredness
  • Anticipatory anxiety
CAUSES
  • Medical illnesses - arthritis, fibromyalgia, hyperthyroidism, gastroesophageal reflux disease, duodenal ulcer, Alzheimer's disease and other dementias, restless leg syndrome, sleep apnea, respiratory diseases, and all painful conditions (e.g., muscle cramps)
  • Psychiatric illnesses - mostly depression, classically associated with early morning awakening, but can also be manifested by initial or middle insomnia
  • Anxiety
  • Schizophrenia
  • Manic disorders
  • Drug induced insomnia - alcohol, caffeine, nicotine
  • Nonprescription drugs - diet aids, decongestants, cough preparations
  • Prescribed drugs - steroids, theophylline, phenytoin (Dilantin), levodopa (Sinemet, Dopar)
  • Obstructive sleep apnea
  • Jet lag (transient)
  • Heavy smoking
RISK FACTORS
  • Chronic illnesses
  • Age over 50
  • Multiple drug intake
  • Obesity

DIAGNOSIS

LABORATORY

N/A

Drugs that may alter lab results: N/A
Disorders that may alter lab results: N/A

PATHOLOGICAL FINDINGS
N/A
SPECIAL TESTS
Diagnosis can be confirmed by the use of polysomnography, particularly if sleep apnea is suspected. This is generally not necessary or practical.
IMAGING

N/A

DIAGNOSTIC PROCEDURES
Insomnia is a self-reported condition

TREATMENT

APPROPRIATE HEALTH CARE

Outpatient

GENERAL MEASURES
  • Transient insomnia
    • Lasts less than three to four weeks
    • Reassurance and supportive counseling are appropriate treatment modalities
  • Chronic insomnia
    • Address the underlying cause: Pain, drugs, depression
    • Avoid alcohol after 5 PM or within 6 hours of retiring because of secondary rebound stimulation
    • Patient should be encouraged to avoid daytime napping and to develop bedtime rituals conducive to sleep
    • A thorough review of the patient's habits, drug intake, diet, and exercise pattern may uncover correctable causes of insomnia
    • Prescribe hypnotics only if the above strategies fail
SURGICAL MEASURES

N/A

ACTIVITY
  • No restriction
  • A daily exercise routine is helpful. Avoid exercise close to bedtime.
DIET
  • Avoid caffeine
  • Avoid heavy, late night snacks (sometimes a light snack before bedtime may help)
  • Avoid alcohol after 5 PM or within 6 hours of retiring, because of secondary rebound stimulation
PATIENT EDUCATION
  • Explain sleep patterns and sleep hygiene
  • Show limitations and noxious effects of drugs used for insomnia
  • Incorporation of appropriate dietary and exercise protocol

FOLLOW UP

PREVENTION/AVOIDANCE

Avoidance, when possible, of all possible causes

POSSIBLE COMPLICATIONS
  • Transient insomnia becomes chronic
  • Increased daytime sleepiness
EXPECTED COURSE AND PROGNOSIS

Should resolve with time. Treatment of underlying symptoms helpful.

MISCELLANEOUS

ASSOCIATED CONDITIONS
  • Obstructive sleep apnea
  • Drug or alcohol addiction and dependence
AGE-RELATED FACTORS

Pediatric: N/A
Geriatric:

  • Exert caution when prescribing benzodiazepines or other sedative-hypnotics to the elderly
  • Educate older patients about age-related sleep changes

Others: N/A

PREGNANCY

Transient insomnia occurs due to discomfort in sleeping positions

OTHER NOTES

L-Tryptophan: formerly widely used - no longer available as a single ingredient

ABBREVIATIONS

N/A

Clinical Investigations

ROLE OF HOMOEOPATHY

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