Urinary tract infection in males

DESCRIPTION
Cystitis is an infection of the lower urinary tract, usually resulting from a single gram-negative enteric bacteria. (See separate chapters for information on prostatitis, pyelonephritis, and non-gonococcal urethritis.)
  • System(s) affected: Renal/Urologic
  • Genetics: No specific genetic pattern
  • Incidence/Prevalence in USA: Not common
  • Predominant age: Increases with age. Uncommon in men under 50. 8 infections/10,000 men, ages 21-50.
  • Predominant sex: Male only (for this discussion)
SIGNS AND SYMPTOMS
  • Urinary frequency
  • Urinary urgency
  • Dysuria
  • Hesitancy
  • Slow urinary stream
  • Dribbling of urine
  • Nocturia
  • Suprapubic discomfort
  • Low back pain
  • Hematuria
  • Systemic symptoms (chills, fever) present with concomitant pyelonephritis or prostatitis
CAUSES
  • Escherichia coli (80% of infections)
  • Klebsiella
  • Enterobacter
  • Proteus
  • Pseudomonas
  • Serratia
  • Streptococcus faecalis and Staphylococcus
RISK FACTORS
  • Benign prostatic hypertrophy
  • Cognitive impairment
  • Fecal incontinence
  • Urinary incontinence
  • Anal intercourse
  • Recent urologic surgery, catheterization
  • Infection of the prostate or kidney
  • Urinary tract instrumentation
  • Immunocompromised host
  • Outlet obstruction
LABORATORY
  • Pyuria
  • Bacteriuria
  • Urine dipstick leukocyte esterase (75-90% sensitivity, 95% specificity) and nitrate (35-85% sensitivity, 70% specificity)
  • Urine culture - 10/high power colonies of pathogens (or counts > 100,000 bacteria/mL of urine) confirms diagnosis (Escherichia coli, Klebsiella, Pseudomonas, other agents). Lower counts can also be indicative of infection, especially in presence of pyuria.
  • Segmented bacteriologic localization cultures
    • VB1 - collect 5–10 mL of urine of patient's initial voiding
    • VB2 - sample of sterile midstream urine is obtained
    • EPS - prostatic massage performed, and expressed prostatic secretion is collected from the meatus
    • VB3 - patient completes voiding and 4th sample is collected
    • Cultures and sensitivity collected from each specimen
Drugs that may alter lab results: Antibiotics prior to culture Disorders that may alter lab results: N/A
PATHOLOGICAL FINDINGS
Depends on site of infection
SPECIAL TESTS
Urologic investigations necessary to rule out other disorders
IMAGING

Intravenous pyelography, cystoscopy, ultrasound

DIAGNOSTIC PROCEDURES

Careful history and physical

ASSOCIATED CONDITIONS
  • Acute bacterial pyelonephritis
  • Chronic bacterial pyelonephritis
  • Urethritis
  • Prostatitis
  • Prostatic hypertrophy
  • Prostate cancer
AGE-RELATED FACTORS

Pediatric: Usually associated with obstruction to normal flow of urine, such as vesicoureteral reflux
Geriatric: Bacteriuria is common in the elderly, appears related to functional status and is usually transient. If asymptomatic bacteriuria is noted, no treatment is needed.
Others: N/A

PREGNANCY

N/A

OTHER NOTES

N/A

ABBREVIATIONS

N/A

PREVENTION/AVOIDANCE
  • Prompt treatment of predisposing factors
  • Catheter use only when necessary. If needed, use aseptic technique and closed system, with removal as soon as possible.
POSSIBLE COMPLICATIONS
  • Pyelonephritis
  • Ascending infection
  • Recurrent infection
EXPECTED COURSE AND PROGNOSIS

Clearing of infections with appropriate antibiotic treatment

APPROPRIATE HEALTH CARE

Outpatient, except for acute illness with toxicity or kidney failure

GENERAL MEASURES
  • Hydration and analgesia if required
  • Discontinue sexual activity until cured
  • Patient with indwelling catheters
    • If asymptomatic bacterial colonization - no need to treat (sterilization of urine not possible and resistant organisms can take up residence)
    • If symptomatic of acute infection - institute treatment
SURGICAL MEASURES

N/A

ACTIVITY

Activity as tolerated.

DIET

No special diet

PATIENT EDUCATION

For patient education materials favorably reviewed on this topic, contact: National Kidney Foundation, 30 E. 33rd Street, Suite 1100, New York, NY 10016, (212)889-2210

Clinical Investigations

ROLE OF HOMOEOPATHY

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