Epistaxis Disease

BASICS

DESCRIPTION
Hemorrhage from nostril, nasal cavity or nasopharynx
  • Anterior bleed: Originates from anterior nasal cavity, usually Little's area (Kiesselbach's plexus) on septum just above the posterior end of the nasal vestibule. The second most common site is the anterior end of the inferior turbinate.
  • Posterior bleed: Originates from the posterior nasal cavity or nasopharynx, usually under the posterior half of the inferior turbinate or the roof of the nasal cavity
  • System(s) affected: Pulmonary
  • Genetics: N/A
  • Incidence/Prevalence in USA: Unknown
  • Predominant age: Less than 10 years and over 50 years
  • Predominant sex: Male = Female
SIGNS AND SYMPTOMS
Usually nostril hemorrhage, however cases of posterior bleed may be asymptomatic or present with hemoptysis, nausea, hematemesis or melena
CAUSES
  • Idiopathic (most common)
  • Traumatic/blunt – nose picking (epistaxis digitorum), low humidity, foreign body
  • Infection – upper respiratory, acute/chronic rhinitis, acute/chronic sinusitis
  • Vascular abnormalities – sclerotic vessels of age, hereditary hemorrhagic telangiectasia, arteriovenous malformation
  • Neoplasm (especially when unilateral)
  • Hypertension (usually in combination with another cause)
  • Coagulopathy – hereditary (e.g., hemophilia), therapeutic or adverse effect of drugs, blood dyscrasias, leukemias, thrombocytopenia or platelet dysfunction
  • Septal perforation
  • Septal deviation (one side is overexposed to dry air)
  • Bleeding originating in a sinus (fracture, tumor)
  • Endometriosis (nasal ectopic endometrium)
RISK FACTORS
Included in Causes

DIAGNOSIS

LABORATORY

CBC, crossmatch for hypovolemic shock or anemia

Drugs that may alter lab results: N/A
Disorders that may alter lab results: N/A

PATHOLOGICAL FINDINGS
N/A
SPECIAL TESTS
As indicated for unusual causes
IMAGING
CT scan if neoplasm is suspected
DIAGNOSTIC PROCEDURES
  • Angiography (rarely)
  • Nasal endoscopy to locate and cauterize bleeding vessel

TREATMENT

APPROPRIATE HEALTH CARE
  • Outpatient (usually). Inpatient for severe hemorrhage.
  • Elderly patient with posterior bleeds and balloon or packing usually requires admission
GENERAL MEASURES
  • Resuscitation as indicated
  • Sedation, analgesic, antihypertensive or anticoagulant reversal as needed
  • Patient should be gowned and sitting, if stable. Gown, gloves, and eye protection for examiner.
  • Attempt to locate bleeding site using headlamp, suction, nasal speculum and assistant.
    Clear nasal cavity of blood with suction, forceps withdrawal of clot or patient blowing nose.
    If bleeding has stopped, rub suspicious areas with wet cotton tipped applicator to identify site.
    Diffuse ooze or multiple sites suggests systemic cause. In cases of posterior bleed try to identify
    as either roof or low posterior site since each has different arterial supply (will be important if
    arterial ligation is necessary).
  • Locating the bleeding site may be difficult if patient presents with bilateral bleed. Usually there
    is only one bleeding site and the blood appears on the other because of:
    • Septal perforation
    • Obstruction of the affected side by pinching or packing
    • Posterior bleed where blood passes behind the nasal septum

    Clues are the side on which bleeding started and a careful examination using suction, headlamp and speculum.

  • Anterior bleed:
    • Place pledget soaked in vasoconstrictor and local anesthetic in cavity and pinch nostril
      for several minutes to stop bleeding by direct pressure
    • Remove pledget and visualize vessel. Cauterize with silver nitrate stick directly on vessel
      with firm pressure for 30 seconds.
    • Alternative chemical cautery includes bead of chromic acid or 25% trichloracetic acid.
      Larger vessels respond better to thermal cautery or bipolar electrocautery.
      Avoid indiscriminate cauterization of a large area.
    • If unsuccessful, apply second dose of anesthetic and place anterior pack using
      1/2 x 72 inch ribbon gauze impregnated with petroleum jelly (Vaseline) or nasal tampons.
      Insert in folding layers with bayonet forceps and nasal speculum. Tape 2x2 gauze over nostril
      as drip catch.
  • Posterior bleed:
    • Traditional posterior packing is still effective if balloon systems fail to control bleeding.
    • Balloon systems: single large balloon (with or without airway tube) or dual-balloon system
      (10 cc posterior + 30 cc anterior). Insert after local anesthesia, inflate per manufacturer’s
      instructions.
    • Foley catheter method: Use 10–14 Fr Foley placed through nostril to nasopharynx. Inflate balloon
      7–15 cc, pull forward, maintain traction, then insert anterior pack. Secure catheter with cord clamp
      and gauze padding, tape remainder over ear.
  • Intractable bleed:
    • Bilateral packing may be required (admission required).
    • Bleeding from roof may be controlled by placing double balloon system with small anterior pack
      above anterior balloon.
    • Intractable bleed will require surgical cauterization or arterial ligation (ideally after visual
      identification of bleeding site). Alternatively, angiographic selective arterial embolization.
SURGICAL MEASURES
  • Arterial ligation for intractable bleeding
ACTIVITY

Bedrest with head at 45 to 90 degrees

DIET

No alcohol or hot liquids

PATIENT EDUCATION

Demonstrate proper pinching pressure techniques

FOLLOW UP

PREVENTION/AVOIDANCE

Liberal application of petroleum jelly (Vaseline) to nostril to prevent drying and picking. Humidification at night. Cut fingernails.

POSSIBLE COMPLICATIONS
  • Sinusitis
  • Double balloon systems tend to migrate posteriorly; if the anterior balloon breaks, the patient may obstruct the airway with the migrated posterior balloon. Prevent by placing an umbilical cord clamp across the end of the tubing at the nostril after inflation.
  • Septal hematoma or abscess from excessive trauma during packing
  • Septal perforation secondary to aggressive cauterization
  • External nasal deformity secondary to pressure necrosis from the anterior component of posterior packing
  • Mucosal pressure necrosis secondary to high balloon inflation pressures
  • Cocaine, lidocaine toxicity
  • Vasovagal episode during packing
EXPECTED COURSE AND PROGNOSIS

Good results with proper treatment

MISCELLANEOUS

ASSOCIATED CONDITIONS

In the elderly - hypertension, atherosclerosis and conditions that decrease platelets and clotting functions

AGE-RELATED FACTORS

Pediatric: More likely anterior bleed
Geriatric: More likely posterior bleed
Others: N/A

PREGNANCY

N/A

OTHER NOTES

N/A

ABBREVIATIONS

N/A

Clinical Investigations

ROLE OF HOMOEOPATHY

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