Irritable Bowel Syndrome Disease

BASICS

DESCRIPTION
Altered bowel habits, abdominal pain, gaseousness, in the absence of organic pathology (divided into four types):
  • Alternating diarrhea with constipation
  • Diarrhea predominant
  • Constipation predominant
  • Upper abdominal bloating and discomfort
  • System(s) affected: Gastrointestinal
  • Genetics: Unknown, but more common in families of patients
  • Incidence/Prevalence in USA:
    • Unknown, but 50% of gastrointestinal visits, and second to upper respiratory infection as cause for lost workdays
    • At least 15% of population (uncommon in children and early teens)
  • Predominant age:
    • Late 20's, rarely in late teens
    • If over age 40, other disease more likely
  • Predominant sex:
    • Female > Male (2:1) in the US
    • In other parts of the world - Male > Female
SIGNS AND SYMPTOMS
  • All present in most patients but not with every episode
  • Abdominal pain, usually lower quadrant, relieved by defecation
  • Mucus in stools
  • Constipation
  • Diarrhea
  • Distention
  • Upper abdominal discomfort after eating
  • Straining for normal consistency stools
  • Urgency of defecation
  • Feelings of incomplete evacuation
  • Scybalous stools
  • Nausea, vomiting (rarely)
CAUSES
Unknown but patients show some gut motility abnormalities with increased response to stress and stimulants, and increase in the 3 cycles/minute smooth muscle contractions
RISK FACTORS
  • Other members of the family with the same or similar gastrointestinal disorder
  • History of childhood sexual abuse
  • Sexual or domestic abuse in women

DIAGNOSIS

LABORATORY
  • As needed to rule out other pathology
    • ESR
    • CBC
    • Stool for ova, parasites and culture

Drugs that may alter lab results: N/A
Disorders that may alter lab results: N/A

PATHOLOGICAL FINDINGS
All labs normal except for sigmoidoscopy
SPECIAL TESTS
Not needed for diagnosis
IMAGING
  • Barium enema, if indicated is usually normal
  • Small bowel series
DIAGNOSTIC PROCEDURES
Sigmoidoscopy (often normal), can show spasm that reproduces pain and increase mucosal folds

TREATMENT

APPROPRIATE HEALTH CARE

Outpatient

GENERAL MEASURES
  • Heat to abdomen can help
  • Biofeedback may help
  • Reduce stress
SURGICAL MEASURES

N/A

ACTIVITY

As normal

DIET
  • Increase fiber - may make some patients worse
  • Avoid - large meals; spicy, fried, fatty foods; milk products, carbohydrates
PATIENT EDUCATION
  • Many materials available nationally and locally
  • Stress the organicity of the disease versus any psycho-social interpretation
  • Teach patient to avoid problem stimulants

FOLLOW UP

PREVENTION/AVOIDANCE

See Diet

POSSIBLE COMPLICATIONS

N/A

EXPECTED COURSE AND PROGNOSIS
  • No progression to cancer or inflammatory disease
  • Expect recurrences, when under stress, throughout life. Frequency lessens as age increases.

MISCELLANEOUS

ASSOCIATED CONDITIONS
  • Migraine
  • Bladder frequency
  • Nocturia
  • Urgency
  • Fecal incontinence
  • Fibromyalgia
  • Dyspareunia
  • Depression
  • Stress incontinence
AGE-RELATED FACTORS

N/A

Pediatric: N/A
Geriatric: N/A
Others: N/A

PREGNANCY

Anecdotal information implies that irritable bowel syndrome gets worse in pregnancy. But there are no increased risks to fetus or mother.

OTHER NOTES

Must not give patients the impression that this is a psychiatric illness

ABBREVIATIONS

IBS = irritable bowel syndrome

Clinical Investigations

ROLE OF HOMOEOPATHY

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