Otitis Media Disease

DESCRIPTION
Inflammation of the middle ear
  • Acute otitis media (AOM): Usually a bacterial infection accompanied by viral upper respiratory infection; rapid onset of signs and symptoms
  • Recurrent AOM: 3 or more AOM in 6 months, or 4 or more AOM in 1 year
  • Otitis media with effusion (OME): Persistent inflammation manifested as asymptomatic middle ear fluid that follows AOM or arises without prior AOM
  • Chronic otitis media with or without cholesteatoma
  • System(s) affected: Nervous
  • Genetics: May be influenced by skull configuration or immunological defects
  • Incidence/Prevalence in USA: (Incidence) By age 7 years 93% of children have 1 or more AOM; 39% have 6 or more AOM; after AOM 10 to 20% still have OME 3 months later
  • Predominant age: Peak incidence age 6-18 months; declines after age 7 years; rare in adults
  • Predominant sex: Male > Female (for AOM and recurrent AOM)
SIGNS AND SYMPTOMS
  • AOM:
    • Earache
    • Fever, although more often afebrile
    • Accompanying URI symptoms
    • Decreased hearing
    • Otorrhea if eardrum perforated
    • Eardrum mobility decreased (as observed by pneumatic otoscopy)
    • Eardrum bulging, opaque, often yellowish or inflamed. Redness alone is not a reliable sign.
  • AOM in infants:
    • May cause no symptoms in the first few months of life
    • Irritability is sometimes the only indication of earache
    • Eardrum bulging, opaque, often yellowish or inflamed. Redness alone not a reliable sign.
  • OME:
    • Usually asymptomatic
    • Decreased hearing probably universal, but not always measurable, and rarely appreciated by parents
    • Eardrum often dull, but not bulging
    • Eardrum mobility decreased (as observed by pneumatic otoscopy)
CAUSES
  • AOM: A preceding viral upper respiratory infection produces eustachian tube dysfunction that is thought to promote bacterial infection via eustachian tube. Bacteriology:
    • Pneumococci: 30-35%
    • Haemophilus influenzae: 20-25%; 40% of these produce beta-lactamases that hydrolyze amoxicillin and some cephalosporins
    • Moraxella (Branhamella) catarrhalis: 10-15%; 90% of these produce beta-lactamases that hydrolyze amoxicillin and some cephalosporins
    • Group A streptococci: 3%
    • Staphylococcus aureus: 1-2%
    • Sterile/non-pathogens: 25-30%
  • OME:
    • 20-40% silent bacterial infection
    • Eustachian tube dysfunction thought important
    • Allergic causes rarely substantiated
RISK FACTORS
  • Day care
  • Formula feeding
  • Smoking in household
  • Male gender
  • Family history of middle ear disease
  • AOM in 1st year of life is a risk factor for recurrent AOM
  • Sibling history of otitis media
LABORATORY

WBC higher in bacterial AOM than in sterile AOM
Drugs that may alter lab results: N/A
Disorders that may alter lab results: N/A

PATHOLOGICAL FINDINGS
N/A
SPECIAL TESTS
  • To document the presence of middle ear fluid - tympanometry, acoustic reflex measurement or acoustic reflectometry
  • Hearing testing helpful to assess the need for early surgical intervention in OME
  • Nasopharyngoscopy
IMAGING

N/A

DIAGNOSTIC PROCEDURES
Tympanocentesis for microbiologic diagnosis recommended for treatment failures, may be followed by myringotomy
APPROPRIATE HEALTH CARE

Outpatient except when surgery is indicated

GENERAL MEASURES
  • AOM: Outpatient except for febrile infants < 2 months
  • May use watchful waiting approach, treating symptoms without antibiotics for first 2-3 days. If symptoms persist, then amoxicillin is first line treatment.
SURGICAL MEASURES
  • OME: Referral for surgery if: > 4-6 months bilateral OME, and/or > 6 months unilateral OME, and/or hearing loss > 25 decibels
  • Recurrent AOM: Referral for surgery if > 2 or 3 AOM while on chemoprophylaxis
  • Tympanostomy tubes and adenoidectomy: Effective surgical procedures for OME and recurrent AOM, but not in all cases
ACTIVITY

No restrictions

DIET

No special diet

PATIENT EDUCATION

N/A

PREVENTION/AVOIDANCE
  • Breast-feeding decreases incidence of AOM
  • Eliminate cigarette smoking in the household
POSSIBLE COMPLICATIONS
  • AOM: Perforation/otorrhea, acute mastoiditis, facial nerve paralysis, otitic hydrocephalus, meningitis
  • OME: Hearing loss. Extent and significance of impaired speech and language is controversial.
  • Recurrent AOM and OME: Atrophy and scarring of eardrum, chronic perforation and otorrhea, cholesteatoma, permanent hearing loss, chronic mastoiditis, brain abscess and other intracranial suppurative complications
EXPECTED COURSE AND PROGNOSIS
  • AOM: Symptoms usually improve in 48-72 hrs; OME following AOM resolved in 90% by 3 months
  • OME: Approximately 50% resolve after 8 weeks of observation
  • Recurrent AOM and OME: Usually subside in school age children; only a small percentage have complications
ASSOCIATED CONDITIONS
  • Upper respiratory infection
  • Bacteremia
  • Meningitis
  • Allergies
AGE-RELATED FACTORS

Pediatric: Primarily a pediatric disease
Geriatric: N/A
Others: N/A

PREGNANCY

N/A

OTHER NOTES

In first few months of infancy, the eardrum is normally at an angle and less mobile in older adults

ABBREVIATIONS

AOM = acute otitis media
OM = otitis media
OME = otitis media with effusion

Clinical Investigations

ROLE OF HOMOEOPATHY

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